In collaboration with Drs. Clare Haystead in the Department of Radiology at DUMC, we have been investigating the benefit of using elevated acoustic output in hepatic harmonic imaging and in ultrasound shear wave harmonic tracking. We have developed custom sequences to acquire real B-mode pulse-inversion harmonic images, as well as M-mode and shear wave sequences with low and high Mechanical Index (MI) values. We are currently in the process of a clinical study to evaluate the image quality improvement using elevated acoustic output with patients undergoing general abdominal ultrasound exams.
- Deng Y, Palmeri M, Haystead C, Nightingale K "Evaluating the Benefit of Elevated Acoustic Output in Harmonic Motion Esetimation in Ultrasonic Shear Wave Elasticity Imaging", UMB, 44(2): 303-310, 2018. PMCID: PMC5743577.
- Deng Y, Palmeri M, Rouze N, Haystead C., Nightingale K. "Quantifying Image Quality Improvement Using Elevated Acoustic Output in B-Mode Harmonic Imaging", UMB, 43(10): 2416-2425, 2017. PMCID: PMC5580090.
- Deng Y, Palmeri M, Rouze N, Nightingale K. “Quantifying the benefit of elevated acoustic output in harmonic imaging”. Proceedings of the 2015 IEEE Ultrasonics Symposium, Taipei, 2015.
- Deng Y, Palmeri M, Rouze N, Rosenzweig S, Abdelmalek M, Nightingale K.“Analyzing the impact of increasing Mechanical Index (MI) and energy deposition on shear wave speed (SWS) reconstruction in human liver”, Ultrasound in Medicine and Biology, 41(7): 1948-1957, 2015. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461469/
This research has been supported by NIH grants R01EB002132 and R01EB022106