Longitudinal Study of SWEI Metrics in Healthy Muscle is conducted and published!

Shruthi Srinivasan and co-authors published a paper in the Journal of Ultrasound in Medicine and Biology entitled "Longitudinal Assessment of Quantitative Metrics for Skeletal Muscle Health Using 3D-Rotational Shear Wave Elasticity Imaging in the Vastus Lateralis." 

In this paper, authors quantified the low variation of SWEI metrics-of-interest (such as shear wave speed, anisotropy of the muscle, and the increase of those parameters with applied knee flexion) across 3 months in the vastus lateralis of healthy participants. Among all metrics analyzed, quantified coefficient of variation was <10% on average, which can have broader implications for longitudinal monitoring of neuromuscular disease progression. Congratulations to Shruthi and co-authors!

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Shown in the figure is shear wave speed parallel (red) and perpendicular (blue) to the muscle fibers, and fractional anisotropy measurements at multiple knee flexion angles - averaged across 3 months and across 10 participants.